The loss of weight associated with a chronic illness is referred to as cachexia. Unexpected, unintentional weight loss is a common symptom of illness and should be evaluated by a healthcare professional.

Poor management of Type 1 Diabetes can be a cause of significant weight loss, as high blood sugars release ketones, which break down fat and muscle to be burned as energy because lack of insulin prevents the body from using the sugar in the blood stream as energy.

Medications, lack of fluid intake, or illnesses such as diabetes can trigger fluid loss.

Weight loss may refer to the loss of total body mass in an effort to improve fitness, health, and/or appearance.

Therapeutic weight loss, in individuals who are overweight, can decrease the likelihood of developing diseases such as diabetes. Overweight and obese individuals are also at greater risk of health conditions, such as type 2 diabetes,coronary heart disease, high blood pressure, and osteoarthritis. For healthy weight loss, a physician should be consulted to develop a weight loss plan that is tailored to the individual.

Weight loss occurs when an individual is in a state of negative energy balance. When the human body is losing more chemical energy in work and heat than it is gaining from food or other nutritional supplements, it will catabolise stored reserves inside the body.

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